Workplace violence (WPV) is a growing concern globally, particularly among medical professionals like nurses, who face heightened risk due to their close patient contact. A survey conducted by the Ontario Council of Hospital Unions and the Ontario division of the Canadian Union of Public Employees in 2019 revealed alarming rates of physical violence experienced by personal support workers and registered practical nurses in Northeastern Ontario. This study aims to explore nurses’ perceptions of violence in acute-care settings in the region and identify challenges and necessary improvements to prevent WPV. Conducted using interpretive description qualitative methodology guided by the Haddon matrix conceptual framework, the study involved 14 registered nurses participating in virtual focus groups across three patient care units. The overarching theme, “nurses surviving violence in acute-care settings,” emerged alongside key themes such as differing perceptions of violence thresholds among nurses, the vulnerability of nurses, and the need for changes to the status quo. Findings underscore the daily occurrence of violence against nurses, emphasizing that it should never be justified. The study advocates for comprehensive education, training, and support initiatives involving hospital staff, law enforcement, the community, and the public to effectively prevent WPV.