Does diphenhydramine impair evaporative heat loss during physical activity in temperature conditions?


Dr. Nicholas Ravanelli, Dougie Newhouse

The prevalence of allergic respiratory diseases, such as allergic rhinitis (AR), has dramatically increased worldwide with global warming being a significant contributing factor. AR causes severe disruptions to one’s quality of life, sleep, and productivity. Nearly 1 in 4 Canadians have allergic rhinitis (e.g. hay fever) and up to 78% of individuals in specific work environments develop occupational rhinitis with the primary treatment strategy being over-the-counter anti-histamine medications.